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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '492dff3d899211e0c7d85ef66a3f400220f3adf8b0c40180c5df2eb270afc45d' 
  AND token = 'XjVIfjKihySCzi6kiqp0pMEMqrbTQoyAwvCsgZs7Wo8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}