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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc181813d19e8fb252e007b758cb0a7c2ec70da6bc49a269e7e14c8d1d82a005' 
  AND token = '8ZU4oZmcVXginGLBUUC71Y7BF9ghdYJ4OMhiKCIQqJ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}