SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c5831cae303ca7d58dcbeccbb43966e272a7b73f7f5bd95100222b7559ba85f' 
  AND token = '1YrSFbMlWYFl1UBaXMX0t+QoF1dSvri1TM68Ziu8gGY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}