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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '372590e227dac078fa0c5c70b09c6898bfb645b152b6d1af8645621277d9e71a' 
  AND token = 'BFUTIOYTS/tWMq5IKDZl4n41Bewtp8TXy9q8yG9Ehl8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}