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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2a29974874b5bfa48c6717a7b757481f2cd34837cb8fb53a19fd93f968c8198' 
  AND token = 'P8u489a+LoirZ6T0vOSgYBmkfYN627rO5dfhFYrY8b8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}