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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b597bc34f8672f34faf45eb29f8dff53ff99d44a7ff4297b5138a60303c0dbfa' 
  AND token = 'vSk/HdyG31B+bKaS637xA+GS3aHBeNGGjdjU212cbQI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}