SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '747d6a3e9d17f5ee47ec3528786bea6d76f711534ac693bcc7e00816e5e32598' 
  AND token = '6wuSaNSBIl3oFH3QX3V/nfmlSLlkytQqTBGgBD0RY0s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}