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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44633b0a017574738371e80f38103145a5310ba61244c1002157e69f1dc94642' 
  AND token = 'Rp/TkxoQfQmcG5myZDSFfzMHh+m1SbaFxlhNpV+mjXU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}