SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c943f8555bd5fce19fe7d070e7bd59e4658fb965bca00cfa1aead3d3b36c2cb0' 
  AND token = 'VyFLmP6vDhL7494L9aFdPNPtUiR51HM2TijCpRxc9uo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}