SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '89179c907b001f5818d90d7e350acff27b38df5fdd2d41927f673949ebb8c221' 
  AND token = 'urE8bFw/eHJ16fr/+r/L7uXTJi6wywC/z/wffmRMJsI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}