SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e7d4a5861c0973da76bc7d3b2a180365381e0af15f2ea1143fdb866da6cf3b7' 
  AND token = 'I4++SKs0M+kfg0lukxoHBcsNNXIRhN2nfktS2j7bZ7E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}