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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bd659986ccf7f868843d89e069e3c625f2c73a2404c248460913aca46d6d3c91' 
  AND token = 'OKgtuC2hZhvE8OhrYgbCwmkHA6hpRUWUE0XQ68nOnME=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}