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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ae3089d7bef49396a5a9d00e526cff507d39de0e7d9a6c318b77f08e7102b0d' 
  AND token = 'HkbJ6nSnjzVnEyN9tYgAAGz5JO+BcGrWFf4z8Kt8zBo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}