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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f607cea227c1821fc0271be8049f6b6f926a3f003486d373f0121b276461a1e' 
  AND token = 'pcAsrjWA+vQFeZNyGx5c1P2/AgMn8UpIyzM7zqlZjS0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}