SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66ff435516861a65f11e7e04d3c3dea084a4cd57c2715d855c95cea0999f0be9' 
  AND token = 'QyqZzddUDqTNoYLXl1Os/YWU7ykfMTje6pJAZyouRPY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}