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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15f86070f646c037a79dde0cf77fb524d504a6cc943db586f8e65f6478eacc91' 
  AND token = 'HPU1iun7MLpZSVN7oOz3OnyLLYZSXKcu4OlVa6559Tc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}