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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aa779c70bc10299bd7d959d185c93c6e648f80d6e3c00c79587e661264141ea7' 
  AND token = '6+QHH1uN5f3JUrbk1oGqwlNegnqYp2HFk7moDeBvDzs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}