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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1af8a131f8bff371129a2821489c292be26ebc1dff493e123767b08ec4771c2a' 
  AND token = 'RHH7ZFlAZ9OVfyweA+/WxNqcr1bSjebfIzFvD9mwjjM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}