SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f116913e57fd40ceb94a4d0743ae3a7a654c9bc1969088e7f78356f44af8228' 
  AND token = 'yyhk0WWLxI2Vq/sOZ/6MhoTojalxw9LaUR5WblevQRg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}