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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33b72ceea2319e47c4fbd3d3b7d3117296f4a8a94a846b2bc649849a4ae3f633' 
  AND token = 'R+mH3tPDFy4UAi6MtYlKGQOP2+40d57PvmUPYn/q2DY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}