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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '644d9345a90e8362d2e29e3d95e017b7187325dd22f015bc131e4b2665b904d8' 
  AND token = 'gfV3UUf1MqwCiXKRwfcD6Mt2PxISmw6z1vUIxjeK/z4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}