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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4df9de675ff70ca08e7c3e51253b19c19d01009c759b348fbb2dd9a8a7124b61' 
  AND token = 'YTJ/5OC0tijEOqdxPNgMXJTMn4XUC5gj+CTJ0ZvC+8U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}