SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cdbd4ec1a2c0285b7376ec81ed9a0f0be5a757c503c2b356be08f9baba58d57' 
  AND token = 'H2sXoYw+HPOrTswYCKM9DsJqRTXWoznUHo5IHBKM0js=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}