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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72b483ff89433e5b47254c238a2c8039ac7f70256ac8643c7c7c3c7297ec930c' 
  AND token = 'JWOWSqYQwhzMKMPzNeMS/4ElcfBIv5c5mT2dC5NE+UE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}