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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '83c8132a525f21aaa651ce6707bb78b001650260454a19e45bbd7d00a64a3ea4' 
  AND token = 'ImEx7cCy0WQVlQLHFVL01v+Lo7Fv9oq/BiTGRKmdfsA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}