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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aec09154861c3fc995a9cafb154249322b2e847a3c6b9bdb671bb52d0e0b9279' 
  AND token = 'j4bTgVmC97BIlXR0myRR8erIyOopHykqOFis9tU971I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}