SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d48607eb24ff7adb5495a0f61abad33c9fc6b515490c36cdaa6578aa10485e8' 
  AND token = '9AnF06avtePG8Tf7izdce5QX+0UDflW746gK4SyDT/w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}