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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '646552628e4342f3efa40a06ebf1dee8b8920096e8fcc5735e20a32e0ee08f86' 
  AND token = 'qH8VeLlQ+xrXqOOBzZGZ20H5tlIgGLHzxTVSTBPRvg4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}