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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88387505685a6207d36013f80f5299963afa1c6d7d68a9d68d4c03ac6c6a0bf1' 
  AND token = 'GThQglNVOx+/fKqtIap3sBV4iEy1a9VxPn4y8678ukI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}