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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '639fc9a4dab351848d2131da83d988da7e849bdd9048322ace3b6c982d2d0bfb' 
  AND token = 'HHYCf1JbPe/v8R0SZenPIiQ2HtRm2l/bg8wOXf8uoaI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}