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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8357edad11249ea959b51bb2e843f6efb5b3336a0a327d3af15bb88b8c61a2a9' 
  AND token = '1TP6JynmXXBcnclNf0u7fNZ4t46NjDHKbh36UEIQ8X4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}