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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6b8fc1f286db6fd8140a482afe1229a4425ecc27ea003ce14ab6da9c4dadd69' 
  AND token = 'Gz5dwfuJWJEnve27Lbd0SwBAvO/5zDpSozbxAbexpeg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}