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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '219d201ad69f9d5442717e2decb5fa44fb320cd282ac0adaea268c8003e15264' 
  AND token = 'U7uKdYXgd5p7KSmS2Lrw9RZTR6z+PivkHSxhJnd3KRw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}