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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45505415eea2bbe05a0fe59bbfc070212baa9e67710e875bcd518e635a56854c' 
  AND token = 'DWgbH/r84T3xvQJ57niD5vtSNMFgMo57xXVrCYIZPDw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}