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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50c891aab769213f5b61d05e8ad8ea9b58c2860cdf5b2ceb615505001b102938' 
  AND token = 'KWO7PoHe12iduwQC3F8/NTi0vEG7CwRvvZU5u93Kbwc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}