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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea74e5b51fe403c0a16f0c29961983031965d370b09c8c6f09231c7b2c7e5430' 
  AND token = 'FZuXw4KnfWouUKxe75l4T3TAoJh+ELxZ8Edl2uwzOtA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}