SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c651cbfd73823eeeb1cef848700dbba2b15a6fe5e7ef857b15381815e61f45c' 
  AND token = 'psOKTtyjuDfTMNo1XRixXKYm8UhvdDO3e6c4XpN/gZ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}