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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '378d80de1ccdb02654eafca8250d97ce88df8f5d988562d35b2b974a7c078f76' 
  AND token = 'FHLyPY8Aa7qKtdyiKpj0+2i3y1Aq8DBUk2NZWMwJT/c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}