SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7fb06310033b81f53c36eb4caf2378c863a6bd1fa5ee03485aaabd2e2a450ae' 
  AND token = 'EQF53X2qwgX8NsZmgv3/A0KBa7K+IlChUvOkxmlBSNI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}