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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cbe85d7b74bf8d0490bb65d03a69f376512c1d4940ad5d4475fb6fd39564f407' 
  AND token = 'S1SkhifEL7vEXsJR0aoG8j+qi8NR3ZF5u93/ygOo3A0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}