SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0246cfe244557ca229b3b9accd5c4324a225940cc60530c83c5efe521013142' 
  AND token = 'px2s+0HqhPmkGHVBJWpuhA/NHFy9sPao0dYuA0vszHc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}