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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2971542d3390f433cf1432be3165f8e4c376d35053b6044f0caab86a95b2373f' 
  AND token = '8rr1w5IoyHBLDrPBsq8Xb93UsKmhdnYHy3GSM2/kUig=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00066

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}