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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f648fd832927fd0e2ca37d717e4dbabb783fb05691e62dddd155c86043b67b4' 
  AND token = 'Ic85XXUgZv1dX2ilICTH0w5KbZm4ph8XFf+msOXKQ80=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}