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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a40fd36b60b58e5d9ba6f868de03b505c2ff8fc1ad780ceae072aa2337f3fd61' 
  AND token = 'txEzgMQjtvKmsQ37BHbcvAaNrkxxlHTAxPZtgWEINYw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}