SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1022ee2b0bcb9fae51ce6b12a22511f7ccedafa7e7e8cd2d915df9d3dc323086' 
  AND token = 'CpGskdaXlSbPPOwY6VL8GK/ouw8Fcz4wc2sghVdLSZQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00090

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}