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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4913d66dd499909c92071180cf9b0f9f174ecf14bff7aebe09c53f1e3e3be868' 
  AND token = 'FL/MWrYfeecKOdgPhg6Oo5t0l+YcLgyzNPuSPBx5QAI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}