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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad0dfa4a82bc693c796c9fb8dca8ebd329913f0a2ca2e42d0b406553ccaab93c' 
  AND token = 'HniCkNjkF3qlkYQaiyhI1XBAXMRyOEo1gps3lWeL1uE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00065

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}