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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15562ac141e6e99646a293aa85dff302c810e19ef3619d44778a10fdb5bc2dc1' 
  AND token = 'vSBR/juiG6WyrQd+BCHBwUPq3/UaQk0V0QEkbPzNck4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}