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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b144dfc4c455b5f959abcce96d75d04a7d5f4178699d9354fdffa08f0078fd5' 
  AND token = '/SwNM2rAzNnaXm6Z2neDQFf2d4xvYIGUZzZ7KAUKHPY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}