SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac25059f4e54f86a076bc830a081e6611cf3450a72c50870433ed28342a6be5e' 
  AND token = 'p4R1woI/EhtY6X4N+Wq63Xpl3aJJisKwYOBjFXGqJIw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}